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Denagard 12.5% Solution (Elanco Animal Health)

42

Description
Tiamulin 12.5% solution for pigs, chickens and turkeys

Primary Package
Bottle 1 lit

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SKU: 6 Categories: ,

Description

Tiamulin hydrogen fumarate solution.

For oral administration in the drinking water of pigs, chickens and turkeys.

Presentation:
An aqueous solution containing 125mg tiamulin hydrogen fumarate per ml. The solution also contains methylparahydroxybenzoate (0.9 mg/ml) and propylparahydroxybenzoate (0.1 mg/ml) as preservatives.

Uses:

Actions:
The following organisms show sensitivity to tiamulin hydrogen fumarate in vitro:
Brachyspira: Brachyspira hyodysenteriae, B. pilosicoli.
Mycoplasmas: Mycoplasma hyopneumoniae, M. hyorhinis,
M. hyosynoviae, Ureaplasma spp, M. gallisepticum, M. synoviae,
M. meleagridis.
Gram-positive: Staphylococcus spp., Streptococcus spp., Arcanobacterium pyogenes.
Gram-negative: Pasteurella spp., Klebsiella pneumoniae, Actinobacillus (Haemophilus) spp., Fusobacterium necrophorum, Bacteroides spp., Campylobacter coli, Lawsonia intracellularis.

Indications:

Pigs:
For the treatment, prevention and control of swine dysentery caused by Brachyspira hyodysenteriae and complicated by Fusobacterium and Bacteroides spp.

Chickens:
For the reduction in the severity of disease caused by mycoplasmas.

Turkeys:
For the reduction in the severity of disease caused by mycoplasmas.
Dosage and administration:

Pigs:
The dosage of Tiamutin 12.5% Solution is 8.8 mg of the active substance per kg bodyweight daily (equivalent to 10 ml of the product per 142 kg bodyweight) administered in the drinking water of pigs for 3 – 5 days depending on the severity of the infection and/or the duration of the disease. The contents of each 1 litre bottle will treat 188 pigs of 25kg bodyweight for three days or 114 pigs of 25kg bodyweight for 5 days. To ensure an intake of 8.8mg/kg daily, Tiamutin 12.5% Solution may be administered in one of two ways.

Tiamutin 12.5% Solution may be administered in approximately one half of the daily water requirements to ensure consumption of the correct dose. Unmedicated water should be provided each day after the medicated water has been consumed. The dosage rate, calculated on a liveweight basis, is equivalent to 10 ml per 142 kg bodyweight.
Tiamutin 12.5% Solution may be administered continuously at a level of 60 ppm of active substance in the drinking water as the only source of drinking water. The daily requirement should be added to the drinking water at the rate of 9.6ml solution per 20 litres (4.5 gallons) of water.
Where a water medicator is used, the appropriate stock solution should be made up according to the makers instructions.

Chickens:
The dosage for chickens is 25mg of active substance per kg bodyweight (equivalent to 100ml of product per 500 kg bodyweight). Tiamulin should be administered at 0.025% in drinking water (2ml product per litre water) for 3 – 5 days and will provide approximately the following daily dosage of tiamulin depending on the age of the bird:
Day old chick: 125 – 150 mg/kg bodyweight
4 week old broiler: 30 – 50 mg/kg bodyweight
10 week old pullet: 30 – 45 mg/kg bodyweight
Layer: 25 mg/kg bodyweight

Turkeys:
The dosage for turkeys is 25mg of active substance per kg bodyweight (equivalent to 100ml of product per 500kg bodyweight). Tiamulin should be administered at 0.025% tiamulin in the drinking water (2ml product per litre water) for 5 days and will provide approximately the following daily dosage of tiamulin depending on the age of the bird:
1 week old poult: 70 mg/kg bodyweight
4 week old poult: 50 mg/kg bodyweight
8 week old poult: 25 – 30 mg/kg bodyweight
20 week old poult: 25 mg/kg bodyweight
Fresh solutions of tiamulin-medicated drinking water should be made up each day.

Warnings:
Pigs may be slaughtered for human consumption only after 6 days from the last treatment.

Chickens may be slaughtered for human consumption only after 3 days from the last treatment. Nil withdrawal period for eggs.

Turkeys may be slaughtered for human consumption only after 3 days from the last treatment.

Contra-indications:
Do not use in animals hypersensitive to the active ingredient. Animals should not receive products containing monensin, narasin or salinomycin, during or for at least seven days before or after treatment with Tiamutin 12.5% Solution. Severe growth depression or death may result.

In order to avoid interactions between tiamulin and the incompatible ionophores monensin, narasin and salinomycin, the feed mill supplying the feed should be notified that tiamulin will be used and that these products should not be included in the feed or contaminate the feed. The feed should be tested for the ionophores prior to use if there is any suspicion that contamination of the feed might occur. If an interaction does occur, stop tiamulin water medication immediately and replace with fresh water. Remove contaminated feed as soon as possible and replace with feed not containing the tiamulin-incompatible ionophores.

Pregnancy and Lactation:
Tiamutin is suitable for use during pregnancy and lactation.

Pharmaceutical Warnings:
Fresh medicated water must be prepared every 24 hours. Watering equipment should be thoroughly cleaned prior to addition of Tiamutin 12.5% Solution. Do not store above 25°C.

pdf Instructions Leaflet