ESB3 (Elanco Animal Health)
This information summarizes the current status of our knowledge and may differ from the legally binding, country specific use instructions provided with the product. Novartis Animal Health Inc. is not liable for damages or injury caused by the use of its products different from those specified on the pack label.
Oral broad-spectrum antibiotic intended for treatment of coccidiosis and specific bacteral diseases in poultry.
Description and Composition
ESB 3 powder contains 30g Sulfaclozine (= Sulfachloropyrazine) sodium monohydrate per 100g. The powder is freely soluble in water.
ESB 3 is an antibiotic belonging to the group of sulfonamides. Like all sulfonamides, sulfaclozine is a competitive antagonist of para-aminobenzoic acid (PABA), a precursor of folic acid, in protozoa and bacteria.Folic acid is a coenzyme necessary for the synthesis of nucleic acid, hence sensitive species do not multiply in the presence of ESB 3.
ESB 3 is indicated for treatment of coccidiosis in poultry due to infection with Eimeria species, fowl typhoid due to infection with Salmonella gallinarum and fowl cholera due to infection with Pasteurella mutocida .
Dosage and Administration
Dissolve 1g ESB 3 30% per liter water. This provides approximately 50 mg active ingredient, or 170 mg ESB 3, per kg bodyweight. Treat for 3 consecutive days and repeat after a 2 days break if necessary (Shuttle programs like day 1, 3, 5, 7, 9 or 1, 2, 5, 6, 9 have also been found effective).
For coccidiosis in chicken caused by E. tenella and E. necatrix doses of 1.5g to 2.0g are indicated.
For the treatment of cholera and typhoid, doses of 1 to 2 g ESB 3 per liter water for at least 5 days are required.
Chicken: 14 days
Turkeys: 21 days (turkey meat and offal excluding skin: 14 days)
Eggs: 11 days
Special Precautions and Warnings
For use in drinking water of poultry. Prepare fresh water daily.
Avoid underdosing. Sick birds may drink less water than normal. When such birds can be isolated the proportion of ESB 3 in the water can be proportionally increased.
Avoid overdosing. At high ambient temperatures birds drink more water than usual, and thus the concentration of ESB 3 in the water should be decreased.
Formulations and Packages
ESB 3 30% :
Carton with 250g plus one spoon of 10g size
Box with 4 cartons of 250g each
Storage Recommendations and Shelf Life
If stored at room temperature and protected from light and moisture a shelf life of 5 years is given.